SPS-211 IOLs- Monofocal and Bifocal | ASCRS
April 25-28, 2025 | Los Angeles, CA

2025 ASCRS Annual Meeting

SPS-211
IOLs- Monofocal and Bifocal 

Moderator
Omar F. Almallah, MD, ABO
Panelists
Shivani P. Pattnaik, MS
Anam Akhlaq, MBBS

Viewing Papers
Expand a paper title to the right to view the paper abstract and authors. Use the video link to jump to that poster in the session.

Visual Outcomes with Mini-Monovision between a Monofocal Versus an Adjustable Intraocular Lens (Blehm)

Authors

Presenting Author
Clayton G. Blehm, MD, ABO

Paper Abstract

Purpose
To compare binocular visual outcomes between a Light-Adjustable Lens (LAL) and Clareon monofocal/toric IOLs when both are targeting mini-monovision (-1.00 D in the non-dominant eye).

Methods
This was a single center, multi-surgeon, prospective, randomized, comparative study of visual outcomes with mini-monovision between a LAL and Clareon monofocal/toric IOLs. A total of 69 subjects were targeted in each group. Clinical evaluations included monocular and binocular uncorrected and distance corrected visual acuities at distance and intermediate, manifest refraction, monocular and binocular defocus curve, and administration of a questionnaire (PRISQ).

Results
Seventy patients in the Clareon group and 68 in the LAL group completed the study. At three months, Clareon was non-inferior to LAL for all binocular corrected and uncorrected visual acuities except UNVA. Defocus curves were similar (p > 0.05). Spectacle independence for Distance (D), Intermediate (I), and Near (N) were 91%, 87%, and 33% (Clareon) vs 93%, 94%, and 43% (LAL). Patient satisfaction for D, I, and N were 93%, 88%, and 66% (Clareon) vs 91%, 92%, and 72% (LAL). Total ocular HOA was higher in non-dominant LAL eyes (p < 0.001) but similar in dominant eyes. Routine care release took 31.7 � 13.0 days (Clareon) vs 53.9 � 17.5 days (LAL) (p < 0.001). Refractive accuracy was similar.

Conclusion
Results of this study suggest similarly good refractive and visual outcomes for both Clareon monofocal/toric and LAL IOLs when both are targeting same mini-monovision. The Clareon group was able to achieve stable refractive and good visual outcomes sooner after surgery.

Randomized, Multi-Center Clinical Trial to Evaluate Safety and Efficacy of a Novel Cross-Linked Polyisobutylene (xPIB) IOL (Zhao)

Authors

Presenting Author
Yune Zhao, MD
Co-Authors
Hong Yan MD, Hongsheng Bi MD, Xiaobo Xia MD, Mingzhi Zhang MD

Paper Abstract

Purpose
To evaluate safety and efficacy of an IOL made of cross-linked polyisobutylene (xPIB), a novel biomaterial for new generation of foldable IOLs.

Methods
This is a prospective, multicenter, parallel-controlled, randomized clinical trial. Subjects, who were randomly enrolled in 1:1 ratio based on predetermined inclusion/exclusion criteria, underwent one eye cataract removal with either xPIB IOL (test group) or Acrysof SN60WF IOL (control group) implantation. The follow-up schedule was 1 day, 1 week, 1 month, 3 months, 6 months, and 12 months postoperative. The effectiveness endpoint was percentage of subjects with BCDVA ?0.3 logMAR at 6 months. Safety endpoints included postoperative slit lamp and fundus findings, IOP, ECD, AE, SAE, SSI, IOL stability, and device deficiency. Major parameters between two groups were statistically compared.

Results
188 (94 in each group) subjects were enrolled in the trial. The percentage of BCDVA ?0.3 logMAR at 6 months was 100% in both groups. Mean BCDVA was near 0 logMAR in both groups at 12 months. The difference between predicted and residual refractive error was 0.066D (test) and 0.181D (control). The rate of AE was 52.7% (test) and 51.6% (control), while SAE was 6.5% (test) and 7.4 % (control). No difference of AE and SAE during the course of trial, as well as IOP and CED up to 12 months, was found between the two groups. All surgical related responses in cornea, anterior chamber and uvea ceased between 7 to 30 days. No decentration, dislocation, tilt, SSI, and device deficiency was reported.

Conclusion
The IOL made of xPIB material is a highly effective device on correcting vision after cataract removal with an excellent safety profile. It is demonstrated that xPIB IOL had a better residual refractive error against pre-op prediction than Acrysof SN60WF.

Severe Intraocular Lens Tilt Following the Yamane Technique (Yao)

Authors

Presenting Author
Melissa Yao, MD
Co-Authors
Shwetha Mudalegundi BSc, Austin Nakatsuka MD, Neil Kelkar MD, Kevin Eid MSc, MD, Nick Mamalis MD, Liliana Werner PhD, MD

Paper Abstract

Purpose
To evaluate CT Lucia 602 intraocular lenses (IOLs) implanted in cases lacking capsular support, and explanted because of decentration/dislocation with subsequent pathological analysis. The main objectives were to a) document the status of haptics, and b) verify the presence of the �rotisserie� effect.

Methods
13 explanted CT Lucia 602 lenses were included, 12 implanted via the Yamane technique, and 1 that was iris-fixated. Four lenses were explanted between October 2020 and February 2022. Nine lenses, explanted between November 2022 and February 2024 also exhibited severe optic tilt, leading to explantation. A chart review was performed to obtain clinical information from each case. Explanted lenses underwent gross and microscopic examination for haptic status and rotation, in the dry state (room temperature) and after hydration (body temperature).

Results
Time between implantation and explantation was longer for lenses explanted before November 2022 (without severe tilt). Among the 26 haptics evaluated, 15 were deformed, 6 were broken, 2 were detached, and 3 were unremarkable. Four haptics of Yamane lenses explanted between November 2022 and February 2024 showed free rotation within the optic insertion, after hydration at body temperature.

Conclusion
Anecdotal reports of the �rotisserie� effect of CT Lucia 602 lenses implanted via the Yamane technique appeared mostly during the second half of 2022, and suggested that affected lenses were from specific batches, which appears to be consistent with the findings of this study.

In-Vivo Performance of a Novel Monofocal Intraocular Lens with Higher-Order Aspheric Coefficients and Controlled Curvature Change (Hill)

Authors

Presenting Author
Christine B Hill, MD
Co-Authors
Karolinne Rocha MD, PhD, Raman Bedi MD, Marcela Barros MD

Paper Abstract

Purpose
To evaluate the optical performance, in-vivo wavefront analysis, defocus curve (DC), and automated refraction (AR) of a novel monofocal intraocular lens (IOL) with higher-order aspheric coefficients and controlled curvature change.

Methods
This prospective, observational study included 29 healthy eyes undergoing routine cataract extraction and placement of a novel monofocal IOL designed to extend the depth of focus by employing higher-order aspheric coefficients on its posterior surface (Envista Aspire, Bausch & Lomb). Natural pupil size and corneal asphericity were measured preoperatively. Manifest refraction spherical equivalent (MRSE, RSE), uncorrected distance visual acuity (UDVA), distance corrected intermediate visual acuity (DCIVA), distance corrected near visual acuity (DCNVA), DC, AR, and higher-order aberrations were measured postoperatively.

Results
MRSE was within 0.5 diopters (D) of emmetropia in 97% of eyes. Mean UDVA was 20/22, with 93.1% of eyes 20/25 or better. Mean DCIVA was 20/34, with 90% of eyes 20/40 or better. Mean DCNVA was 20/38, with 83% of eyes 20/40 or better. There was no significant difference in MRSE and RSE measured by AR or ray-tracing (p=0.316, 0.271). RSE measured via Hartman-Shack was slightly myopic (-0.24 � 0.45 D, p <0.01). the="" dc="" showed="" 1.25="" d="" of="" continuous="" depth="" of="" focus="" for="" uiva="" of="" 20/32.="" mean="" 4th-order="" spherical="" aberration="" and="" coma="" for="" a="" 4.5="" mm="" pupil="" was="" 0.05="" �="" 0.05="" �m="" and="" 0.15="" �="" 0.05="" �m="" via="" combined="" scheimpflug="" and="" hartman-shack="" device,="" and="" 0.03="" �="" 0.08="" �m="" and="" 0.13="" �="" 0.11="" �m="" via="" double="" pass="">

Conclusion
In-vivo wavefront analysis of eyes implanted with this novel monofocal-plus IOL demonstrate useful near and intermediate vision, while maintaining excellent distance acuity. There were minimal post-operative HOAs. The RSE was emmetropic when measured with two of three devices, and only slightly myopic when measured with the Hartman-Shack device.

Clinical Results and Optical Performance of New Hydrophobic C-Loop Platform Monofocal Intraocular Lens (Eom)

Authors

Presenting Author
Youngsub Eom, MD, PhD
Co-Authors
Kyungmin Koh MD, PhD, MBA, Woong-Joo Whang MD, Jaeyoung Kim PhD, MD, Kookyoung Kim MD, Hungwon Tchah MD, PhD

Paper Abstract

Purpose
To investigate visual outcomes and optical performance of a new non-constant aberration aspheric monofocal intraocular lens (IOL).

Methods
This clinical study enrolled consecutive patients who underwent phacoemulsification with implantation of CT LUCIA 621P (32 eyes of 25 patients) or ZCB00 (38 eyes of 27 patients) IOLs. Monocular uncorrected distance visual acuity (UDVA), uncorrected near visual acuity (UNVA) at 33 cm and 40 cm, uncorrected intermediate visual acuity (UIVA) at 60 cm, and objective optical quality were measured 3 months after surgery. The optical bench test measured the root mean square of the modulation transfer function (MTTRMS) of each IOL at defocus levels between +1.00 D and ?2.50 D at intervals of 0.25 D at varying pupil sizes (2.0�5.0 mm) in 1.0-mm steps.

Results
There was no difference in UDVA, UNVA, and objective optical quality between LUCIA and ZCB00 groups. On the other hand, UIVA was higher in the LUCIA group (0.19 � 0.12 logMAR) compared to the ZCB00 group (0.32 � 0.05 logMAR; p < 0.001). For all tested pupil sizes, the MTFRMS values for both CT LUCIA and ZCB00 IOLs were similar across defocus ranges from +1.00 D to ?0.75 D. However, the CT LUCIA IOL consistently exhibited higher MTFRMS values than the ZCB00 IOL at defocus levels from ?1.25 D to ?2.50 D.

Conclusion
The CT LUCIA IOL provides comparable distance visual acuity and optical quality to ZCB00 IOL, with superior performance at intermediate distances. This study supports the use of non-constant aberration aspheric IOLs in standard cataract surgery settings.

Clinical Evaluation of in-the-Bag Stability of a Novel IOL Made of Cross-Linked Polyisobutylene (Zhao)

Authors

Presenting Author
Yinying Zhao, MD
Co-Authors
Yune Zhao MD

Paper Abstract

Purpose
To evaluate in-the-bag stability of an IOL made of cross-linked polyisobutylene (xPIB), a novel biomaterial for new generation of foldable IOLs.

Methods
This is a prospective, parallel-controlled, randomized clinical study. Subjects, who were randomly enrolled in 1:1 ratio based on predetermined inclusion/exclusion criteria, underwent one eye cataract removal with either xPIB IOL (test group) or Acrysof SN60WF IOL (control group) implantation. The follow-up schedule was 1 day, 1 week, 1 month, 3 months, 6 months, and 12 months after implantation. Postoperative IOL tilt, decentration, anterior chamber depth (PACD), anterior capsule opening area (ACOA), anterior capsule opacification (ACO) and posterior capsule opacification (PCO) were evaluated. UCVA, BCDVA, SE, IOP, CECC was also recorded and compared between the two groups.

Results
38 (19 in each group) subjects were included in this study. All surgeries proceeded successfully. The xPIB IOL showed less decentration than Acrysof SN60WF [0.16(0.08,0.21) vs. 0.18(0.12,0.21) mm] at 1 week after surgery (P=0.032). ACOA reduced during the course of study, with xPIB IOL showing more shrinkage than the Acrysof SN60WF (P<0.05 in="" all="" time="" point).="" this="" anterior="" capsule="" contraction="" (acc)="" was="" negatively="" correlated="" with="" pacd="" change="" from="" 1="" week="" to="" 6="" months="" (r="-0.671," p="0.002)" and="" was="" uncorrelated="" with="" se="" change="" all="" the="" time="" (p="">0.05). The differences in UCVA, BCVA, IOP, CECC, tilt, PAD and ACO between two groups were not statistically significant (P< />

Conclusion
The new xPIB IOL implantation showed excellent in-the-bag stability and visual rehabilitation after cataract removal. Although with higher incidence, the ACC in xPIB IOL group didn�t show any clinical significance or negative impact on visual function.

Visual Outcomes in Enhanced Monofocal IOLs (Schneider)

Authors

Presenting Author
Rachel Schneider, MD

Paper Abstract

Purpose
To measure the range of vision attained with the Aspire and the Eyhance IOLs, and determine if there are any significant differences between the two. Additionally, to compare the range of vision achieved by the enhanced monofocal IOLs to that of a standard monofocal IOL.

Methods
This is a retrospective chart review of consecutive cataract surgeries performed by a single surgeon. Patients with pre-existing conditions that would limit their visual outcome were excluded. Patients who underwent an uncomplicated cataract surgery with or without femtosecond laser with implantation of an enhanced monofocal IOL (Eyhance or Aspire) or a monofocal IOL (Envista, Tecnis, or Clareon) and who had follow-up distance, intermediate and near vision recorded at at least 1 week post-op were included. The average logMar visual acuity at distance, intermediate and near was calculated for each lens type and compared across lenses.

Results
Patients with a plano target 9% Aspire, 35% Eyhance, 41% Envista and 42% Clareon patients = 20/20 UCDVA. 81% Aspire, 95% Eyhance, 72% Envista, 84% Clareon patients had ? 20/30 UCVDA. 36% Aspire,50% Eyhance, 53% Envista, 40% Clareon patients had ?20/32 UInVA. 27% Aspire, 60% Eyhance, 7% Envista, 20% Clareon patients had ? J3 UNVA. Patients with a -0.5 target 0% Aspire, 13% Eyhance, 27% Envista, 17% Clareon patients = 20/20 UCDVA. 28% Aspire, 13% Eyhance, 63% Envista, 67% Clareon patients had ?20/30 UCVDA. 43% Aspire, 80% Eyhance, 83% Envista, 60% Clareon patients had UIntVA ? 20/32. 20% Eyhance patients had J1 UNVA. 43% Aspire, 80% Eyhance, 17% Envista, 20% Clareon patients had ?J3 UNVA.

Conclusion
Eyhance provides better intermediate and near vision compared to Aspire at plano and -0.5 targets. Envista provides similar intermediate vision to Eyhance but less near vision. At -0.5 target, there is the largest decrease in UCDVA with Eyhance. There was worse intermediate vision but better near with Aspire compared to Envista and Clareon.

Visual Acuity after Cataract Surgery with Segmented Bifocal IOLs in Patients with Prior Laser Vision Correction: A Retrospective Review (Hacopian)

Authors

Presenting Author
Alex Hacopian, MD

Paper Abstract

Purpose
The study aimed to evaluate the binocular visual acuity outcomes in patients with a history of laser vision correction who received segmented bifocal intraocular lenses (IOLs) during cataract surgery. In this retrospective chart review, we sought to determine the efficacy and safety of segmented bifocal IOLs in this unique patient population.

Methods
A retrospective chart review was performed seeking patients with a history of laser vision correction who underwent cataract surgery with implantation of segmented bifocal IOLs between January 2023 and December 2024 at a single, private practice ophthalmology center. Preoperative and postoperative visual acuity data, including uncorrected distance visual acuity (UDVA) and uncorrected near visual acuity (UNVA), were collected and analyzed. Patients with ocular comorbidities that could affect visual outcomes were excluded. Follow-up visits were scheduled at 1 week, 1 month, and 3 months post-surgery. Visual acuity was measured using a Snellen chart, and complications were recorded.

Results
TBD

Conclusion
TBD

Interim Analysis of Functional Outcomes after Implantation of Monofocal+ IOLs Inducing Positive Spherical Aberration without Monovision (Chychko)

Authors

Presenting Author
Lizaveta Chychko, MD
Co-Authors
Oliver Hassel MD, Emanuel Reitemeyer MD, Ramin Khoramnia MD, Gerd Auffarth MD, PhD

Paper Abstract

Purpose
To evaluate functional outcomes, including visual performance and patient reported outcomes after implantation of the enhanced monofocal lenses RayOne EMV and RayOne EMV toric RAO210T (Rayner, UK).

Methods
This ongoing prospective study examines the visual outcomes of phacoemulsification combined with RayOne EMV and RayOne EMV toric RAO210T intraocular lens (IOL) implantation in 9 patients (13 eyes) and 8 patients (16 eyes) respectively, with an average age of 72 � 9 years. Postoperative assessments at 1, 3, 6, and 12 months include uncorrected and corrected distance visual acuity (UDVA, CDVA), uncorrected and distance corrected intermediate visual acuity (UIVA, DCIVA) at 66 cm, and uncorrected and distance corrected near visual acuity (UNVA, DCNVA) at 40 cm. Binocular best-corrected defocus curve analysis ranging from +2 to -4 diopters was performed at 3 and 6 months post-surgery.

Results
At 1 month postoperative, mean monocular visual acuity in logMAR was UDVA/CDVA (0.07/-0.01), UIVA/CIVA (0.19/0.20), and UNVA/CNVA (0.41/0.44). At 3 months follow-up, mean monocular visual acuity in logMAR was UDVA/CDVA (0.02/-0.05), UIVA/CIVA (0.23/0.22), and UNVA/CNVA (0.48/0.46). At 6 months, mean monocular visual acuity in logMAR was UDVA/CDVA (0.03/-0.04), UIVA/CIVA (0.19/0.21), and UNVA/CNVA (0.44/0.45). By 12 months, mean monocular visual acuity in logMAR was UDVA/CDVA (0.00/-0.10), UIVA/CIVA (0.27/0.29), and UNVA/CNVA (0.30/0.31).

Conclusion
Preliminary findings suggest satisfactory visual acuity outcomes and reduced photopic phenomena. IOL power calculation and implantation procedures for RayOne EMV and RayOne EMV toric lenses appear straightforward. Ongoing evaluation will further elucidate visual outcomes at 6 and 12 months postoperatively.

Comparative Analysis of Two Monofocal Extended Depth of Focus IOL Optical Performance Under Different Pupil Sizes Using Ray Tracing. (Singh)

Authors

Presenting Author
Laekhram Singh, BSc
Co-Authors
Maria Romero MD

Paper Abstract

Purpose
This study aims to compare the optical performance of two IOL designs: the monofocal extended depth Tecnis Eyance with an anterior refractive surface and the Envista Aspire, with HO coefficients on the posterior surface.Study Evaluates optical performance metrics under pupil sizes (3, 5, and 6 mm) in a prospective study of 80 eyes from 69 patients.

Methods
This retrospective study included 80 eyes from 69 patients who were implanted with either the Tecnis Eyance or Envista Aspire IOLs. The optical performance of these IOLs was assessed using iTrace technology. Key metrics, including wavefront aberrations, modulation transfer function (MTF), Strehl ratio, and extended depth of focus, were measured under varying pupil sizes (3, 5, and 6 mm) in scotopic, mesopic, and photopic conditions. Data were collected during routine postoperative visits. Statistical analysis was performed to compare the optical performance between the two IOL designs, focusing on how each lens responded to changes in pupil size.

Results
In this retrospective analysis conducted in a private practice setting, 80 eyes from 69 patients were evaluated to compare the optical performance of the Tecnis Eyance and Envista Aspire IOLs. Using iTrace technology, wavefront aberrations, MTF, Strehl ratio, and extended depth of focus were assessed across pupil sizes of 3, 5, and 6 mm. The results revealed that the Envista Aspire IOL, with its higher-order aspheric posterior surface, demonstrated stable optical performance across varying pupil sizes Tecnis Eyance IOL showed slight variations in optical metrics, particularly pupil sizes (6 mm), where HOA increased and MTF values slightly decreased but they were not stadistica significant.

Conclusion
The Envista Aspire, with its higher-order aspheric posterior surface, provided consistent optical quality across varying pupil sizes, making it a preferable choice for patients with dynamic pupil responses. In contrast, the Tecnis Eyance showed slight variability, particularly under larger pupil sizes.

Long-Term Visual Outcomes of Extended Macular Vision IOL in Eyes with Macular Disease: Focus on Eyes with Visually Insignificant Cataract (Badala)

Authors

Presenting Author
Federico Badala, MD
Co-Authors
Elena Bona OD, Giulia Devincenzi OD, Kouros Nouri-Mahdavi MS, MD

Paper Abstract

Purpose
To determine the long-term safety and efficacy of an extended macular vision intraocular lens (IOL) implanted in patients with age-related macular degeneration (AMD) undergoing cataract extraction - focus on visually insignificant cataract eyes.

Methods
A retrospective case series examined patients with stable AMD and visually insignificant cataracts who underwent phacoemulsification and implantation of an EyeMax Mono IOL, designed to optimize image quality up to 10 degrees from the foveal center. Inclusion criteria: center-involving macular lesions (e.g., dry AMD, stable wet AMD), stable choroidal neovascularization, and no retinal treatment for 6 months prior. Exclusion: non-functioning retina within 10 degrees of the foveal center. Hypermetropia was targeted in most eyes for magnification with spectacles. Main outcome measures were changes in distant and near visual acuity (CDVA and CNVA) from baseline to the latest follow-up.

Results
113 eyes of 86 patients (mean age 70.3�7.9 years) were included in the study (mean follow-up: 48.3�25.1 months). Mean CDVA and CNVA improved by 0.22 logMAR (13 ETDRS letters) (p<0.001) and="" by="" 0.07="" logmar="" (7="" etdrs="" letters)=""><0.001),>

Conclusion
Visual improvement in patients with visually insignificant cataracts and AMD after phacoemulsification with EyeMax Mono IOL may be influenced by the IOL's optical design. The enhancement highlights the IOL's ability to optimize healthy retinal areas. Prospective studies with a control group are needed to confirm these findings.

Retrospective Real-World Evidence Study: User Experience with an Enhanced Monofocal Intraocular Lens (Patel)

Authors

Presenting Author
Ravi Patel, MD, MBA

Paper Abstract

Purpose
To explore cataract surgeons� real-world experience with an intraocular lens (IOL), enVista ASPIRE� (EA) and/or enVista ASPIRE� toric (ETA), including healthcare provider (HCP) satisfaction and IOL utilization patterns.

Methods
This retrospective, cross-sectional, multicenter study included US cataract surgeons with ?3 years� experience conducting cataract surgery with monofocal and/or toric IOLs, including EA/ETA IOL implantation on ?5 patients. Participants completed a retrospective user-experience survey about their initial experience with EA and/or ETA. The study protocol received exemption from a central institutional review board. Survey outcomes included baseline characteristics, patient outcomes, and HCP satisfaction with EA and ETA. A standardized case report form was used to collect clinical and adverse outcomes. This abstract presents the findings from the retrospective user-experience survey.

Results
Survey responses from 6 HCPs were included in the analysis. They performed a mean�SE of 1950�585 cataract surgeries a year, and had previously implanted a mean�SE total of 84�35 EA and 38�18 ETA IOLs. Of the patients treated in the last year, the most commonly implanted IOL (mean�SE, 37.8�10.6%) was full range of vision. Toric IOLs were used in a mean�SE 42.5�12.6% of cases. On a scale of 0 (very dissatisfied) to 10 (very satisfied), 83% and 100% of surgeons rated their satisfaction with the overall performance of the EA and ETA IOL, respectively, as ?9. Similar ratings were obtained for individual lens qualities and outcomes (e.g., centration, rate of visual disturbances, visual outcomes).

Conclusion
This retrospective multicenter study provides important insights into real-world IOL utilization patterns. HCPs reported high satisfaction overall and across key lens qualities and outcomes with EA and ETA IOLs.

Higher Order Aberrations Induced By Light Treatments in Light Adjustable Lenses. (Abubaker)

Authors

Presenting Author
Rameear A Abubaker, MD, MRCSEd
Co-Authors
William Waldrop MD, Jeremy Bartley MD, Mohammad Bakr MRCSEd, MD, MSc, Ashika Angirekula MD, Margaret Wang MD, BEng

Paper Abstract

Purpose
To determine changes in Higher Order Aberrations induced by light treatments to Light Adjustable Lenses and to correlate the magnitude of HOA changes with best corrected visual acuity pre and post light treatments in eyes treated for distance versus eyes treated for near. The changes in HOAs of LAL with treatments has not been studied prior.

Methods
This was a retrospective chart review approved by the institutional review board. Patients underwent cataract surgery with implantation of LALs were included. Using the�iDESIGN�Refractive Studio images, the�Pentacam�AXL Wave images HOAs were recorded, pre and post treatment refraction and best corrected visual acuity were measured. The study included 250 eyes in the period of 07/07/2023 to 09/01/2024. The primary outcome measured HOAs (vertical and horizontal coma and spherical aberrations) from baseline and correlate it with pre and post treatments' refraction and near and distance best corrected visual acuity.

Results
TBD

Conclusion
TBD

Comparison of Short-Term Clinical Outcomes of Two Monofocal, Aspheric Intraocular Lenses (Han)

Authors

Presenting Author
Jeewon Han, None
Co-Authors
Nahyun Park MD, YooYoung Jeon MD, Hun Lee PhD, MD, Chung Min Lee MD

Paper Abstract

Purpose
To compare compared the visual outcomes and optical quality of two monofocal intraocular lenses (IOLs), CT LUCIA 621P (Carl Zeiss Meditec AG, Jena, Germany) and Eyhance ICB00 (Johnson & Johnson Vision, Santa Ana, CA, USA), by evaluating visual acuity, contrast sensitivity, and higher order aberrations (HOAs) at one month after cataract surgery.

Methods
This retrospective study included 120 eyes from 74 patients who had undergone cataract surgery with either CT LUCIA 621P (LUCIA group) or Eyhance ICB00 (Eyhance group), with 60 eyes assigned to each group. Visual acuity at various distances and defocus curves were measured one month postoperatively. Optical quality was assessed by comparing contrast sensitivity, coma, spherical, and total aberrations using the iTrace (Tracey Technology, Houston, TX, USA), a ray tracing-type aberrometer.

Results
Visual acuity and defocus curves showed no significant differences between the two IOLs one month postoperatively. The LUCIA group showed better contrast sensitivity at higher spatial frequencies: 12 cpd (p=0.001, 1.29 LogCS vs. 1.06 LogCS) and 18 cpd (p=0.002, 0.77 LogCS vs. 0.48 LogCS) unilaterally, and 12 cpd (p=0.026, 1.47 LogCS vs. 1.32 LogCS) and 18 cpd (p=0.029, 0.95 LogCS vs. 0.68 LogCS) bilaterally. Postoperative spherical aberration was significantly lower in the LUCIA group (p=0.002, 0.049 �m vs. 0.076 �m). No significant differences were found in coma or total aberrations.

Conclusion
Visual acuity and defocus curves of the LUCIA and Eyhance groups were comparable at one month after cataract surgery. The superior contrast sensitivity and lower postoperative spherical aberration in the LUCIA group compared to the Eyhance group can be attributed to differences in IOL designs, particularly the continuous power variation patterns.

Comparison of Outcomes of Scleral-Fixated Intraocular Lens Implantation: Transscleral Four-Point Fixation Vs Yamane Intrascleral Fixation (Tan)

Authors

Presenting Author
Shayne S Tan, MBBS, FRCOphth

Paper Abstract

Purpose
To compare long-term functional and anatomical outcomes between 2 scleral-fixed intraocular lens (SFIOL) techniques: transscleral four-point fixation and Yamane suture-less intrascleral fixation.

Methods
This was a retrospective study from Jan 2018 to Dec 2022 in Singapore National Eye Centre. Eyes that had SFIOLs performed for aphakia, subluxed or dislocated intraocular lens or crystalline lens, via Yamane or four-point fixation techniques were recruited. Functional and anatomical outcomes were compared between the four-point and Yamane groups, Yamane fixation in pars-plana-vitrectomised (PPV) vs anterior vitrectomised eyes, four-point vs Yamane fixation in PPV eyes, and high myopes AL?26.0mm) vs non-high myopes. These include post-operative best corrected visual acuity (BCVA), lenticular astigmatism, refractive prediction error and IOL instability (dislocation, decentration, subluxation).

Results
289 eyes of 279 patients were recruited. The mean duration of follow-up was 626.7�455.2 days. Comparing between the four-point and Yamane groups, 55 of 61 eyes (91.7%) and 204 of 228 eyes (89.5%) showed improvement or no change in BCVA respectively; 4 of 61 eyes (6.6%) and 32 of 228 eyes (14.0%) had IOL instability respectively, but there was no significant difference (p >0.05). PPV eyes that had undergone four-point fixation had better final VA than those that had undergone Yamane fixation (logMAR0.25�0.36 vs logMAR0.34�0.59, p=0.05). In eyes with AL?26.0mm, four-point fixation had a significantly lower refractive prediction error (0.56D�0.50 vs 0.72D�0.76, p=0.045) than Yamane fixation.

Conclusion
Both four-point and Yamane fixation showed good long-term functional and anatomical outcomes with low IOL instability rates. PPV eyes that had undergone four-point fixation had better final VA than those that had undergone Yamane fixation. In eyes with AL?26.0mm, four-point fixation showed a lower refractive prediction error than Yamane fixation.

The Application of Monofocal Plus Intraocular Lenses in Enhancing Mini-Monovision (Labuz)

Authors

Presenting Author
Grzegorz Labuz, PhD, BEng
Co-Authors
Ramin Khoramnia MD, Gerd Auffarth MD, PhD

Paper Abstract

Purpose
Standard monovision has long been an established procedure, but it has recently gained renewed interest with the introduction of the RayOne EMV (Rayner), an IOL specifically designed for this configuration. In this study, we evaluated whether employing alternative monofocal-plus approaches could offer similar advantages in mini-monovision.

Methods
In addition to RayOne EMV, Acunex Quantum (Teleon) was used as an alternative approach. Samples with diopter powers of +10, +20, and +30D were included for evaluation. The investigation was conducted on an optical bench featuring a physiological-eye model and polychromatic light. Mini-monovision was simulated by adding the following myopic offset: -0.25D, -0.5D, -0.75D, and -1D, which was combined with a plano target. Simulated visual acuity (simVA) was assessed across various distances, spanning from infinity to 40 cm.

Results
Acunex Quantum produced more extended DoF than RayOne EMV for all IOL powers and offsets, with the latter preserving better VA for higher myopic targets. With -0.25D and -0.50D offsets, both models maintained good simVA, slightly improving DoF. The -0.75D offset reduced monocular vision with 10D, but this effect was less noticeable for higher IOL powers. Over one-VA-line improvement was noted at 50cm for two lenses. Intermediate vision improved with the -1D offset, nearing two lines. Conversely, distance VA was substantially reduced in the 10D groups, but increased IOL powers mitigated this difference.

Conclusion
This study indicates the suitability of monofocal-plus technology for mini-monovision, particularly in patients requiring higher IOL powers. Acunex Quantum appears to extend the intermediate range more compared to RayOne EMV. The observed improvement varied, however, across IOL powers, suggesting potential contributions from spherical aberration.

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