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Moderator
Guy Kleinmann, MD
Panelists
Nick Mamalis, MD
Samuel Masket, MD, ABO
Viewing Papers
Expand a paper title to the right to view the paper abstract and authors. Use the video link to jump to that poster in the session.
Presenting Author
Dagny Zhu, MD, ABO
Co-Authors
Irene Zhou BSc
Purpose
To evaluate visual outcomes and patient satisfaction following bilateral implantation of a non-diffractive, extended depth of focus (EDOF) intraocular lens (IOL) made of a novel hydrophobic acrylic material via a micro-monovision approach in cataract patients.
Methods
A prospective, single-armed study of patients undergoing bilateral femtosecond-laser assisted cataract surgery with implantation of the Clareon Vivity IOL (plano dominant eye; -0.25 D non-dominant eye) was done. Eyes with prior keratorefractive surgery or pathology were excluded. Primary endpoints were binocular best corrected visual acuity at distance (BCDVA) 4m and intermediate (DCIVA) 66 cm at 3 months. Secondary endpoints included binocular uncorrected visual acuity at distance (UDVA), intermediate (UIVA), and near (UNVA) 40 cm, and mean residual spherical equivalent (MRSE), along with binocular defocus curves, patient satisfaction, spectacle independence, and visual disturbances.
Results
46 eyes of 23 patients (mean age 56�6 years) were included. At 3 months, mean BCDVA and DCIVA were -0.07�0.06 and 0.01�0.03 logMAR, respectively. 100% and 78% of patients achieved binocular BCDVA and DCIVA of 20/20 or better. 96%, 100%, and 52% of patients achieved binocular UDVA, UIVA, and UNVA of 20/25 or better, respectively. 83% achieved UNVA of 20/32 or better. MRSE fell within �1.00 D and �0.50 D from target in 100% and 93% of eyes. In a vision quality survey (n=23), 74% of patients did not experience any haloes, glare, or starbursts. 87% of patients reported compete spectacle independence; 96% were satisfied with their vision and 96% would recommend the procedure to others.
Conclusion
Cataract surgery with bilateral implantation of the Clareon Vivity IOL with micro-monovision is a safe and effective approach, yielding high levels of patient satisfaction and spectacle independence with minimal visual disturbances.
Presenting Author
Morgan Micheletti, MD, ABO, FACS
Co-Authors
Kendrick Wang MD, Brad Hall PhD
Purpose
To evaluate patient satisfaction and visual outcomes with extended depth of focus (EDOF) intraocular lens (IOL) implantation in post myopic refractive surgery patients.
Methods
This was a non-interventional, prospective, multi-surgeon study of patient outcomes following successful, uncomplicated cataract surgery in 40 subjects. Patients had history of myopic LASIK or PRK and were bilaterally implanted with the Vivity or Vivity toric EDOF IOLs. Endpoints included monocular and binocular uncorrected and distance corrected visual acuities at distance (UDVA, CDVA), intermediate (UIVA, DCIVA; 66cm), and near (UNVA, DCNVA; 40cm), binocular defocus curve, and administration of a patient satisfaction questionnaire (IOLSAT) and a questionnaire about visual disturbances (QUVID).
Results
A total of 20 subjects (40 eyes) completed the study. Mean binocular UDVA, UIVA, and UNVA were 0.02 � 0.16, 0.14 � 0.13, and 0.24 � 0.14 logMAR respectively. Mean binocular CDVA, DCIVA, and DCNVA were -0.05 � 0.09, 0.11 � 0.11, and 0.25 � 0.15 logMAR, respectively. The percentages of eyes with MRSE and residual astigmatism ? 0.5 D were 95% and 98%, respectively. On the QUVID questionnaire, 0%, 5%, and 0% of patients reported being �Bothered quite a bit� by halo, starbursts, or glare, respectively. On the IOLSAT, patient reported spectacle use was �Never� or �Rarely� in 90%, 75%, and 30% of patients at distance, intermediate, and near, respectively.
Conclusion
Results suggest good visual outcomes at distance, intermediate and functional near vision and high patient satisfaction with Vivity and Vivity toric IOL implantation in post myopic refractive surgery patients.
Presenting Author
Daniel A Black, MD
Co-Authors
Srividhya Vilupuru OD, PhD, Daniel Chang MD
Purpose
To report early real-world results of the TECNIS purely refractive Extended Depth of Focus (EDOF) PCIOL
Methods
This is a multicenter, observational, single-arm study in patients bilaterally implanted with TECNIS purely refractive EDOF IOL. Visual and refractive performance are reported from eight sites. Study is ongoing. 38 patients were implanted in both eyes with the TECNIS EDOF IOL. Binocular uncorrected visual acuity results are reported for distance, intermediate at 66 cm and near at 40 cm in logMAR. Postoperative spherical equivalent refraction, photic phenomena, patient satisfaction, and spectacle independence are also reported
Results
38 subjects (76 eyes) were implanted and had 3-month data available for both eyes at the time of abstract submission. Mean post-op spherical equivalent manifest refraction was 0.15 � 0.46 D. Mean post-op binocular UDVA was -0.11 � 0.08 (20/16), UIVA was 0.08 � 0.08 (20/25) and 0.19 � 0.16 (20/32), respectively. 97%, 97%, 95% of patients did not or experienced a little bothersome halos, glare and starburst, respectively. 89% of patients were mostly or very satisfied with overall vision without glasses
Conclusion
The early real-world results for the TECNIS purely refractive EDOF IOL shows excellent visual outcomes for all distances, with low levels of visual symptoms and high patient satisfaction
Presenting Author
Bharti Kashyap, MS
Co-Authors
Birendra Prasad Kashyap MS, Nidhi Gadkar DNB, MS, Dr.Bibhuti Kashyap DNB, MD
Purpose
To compare Refractive and clinical outcomes of Toric IOL (SN6AT5-T6) power group in Post combined (Phaco Trab) surgery SIA used in Toric IOL power calculation (GrI) and Toric IOL (SN6AT5-T6) power group where post phaco SIA was used in IOL power calculation in cases of Pseudo Exfoliation Cataract (GRII) with Glaucoma & higher Astigmatism ? 2D.
Methods
Prospective randomized comparative, single masking study between Post phaco trab SIA added(Gr1) & Post phaco only SIA(Gr2) for toric iol calculation. 40 eyes in each group included, Single surgeon. Pre op data is comparable. Inclusion Criteria: Age 50-75 yrs, endothelial cell count ? 2000 cells/mm2, IOL power from 20D to 23.5D, Astigmatism ? 2D, capsular bag IOL implantation, No pre and intra op sign of zonular laxity, 5.5mm pupil dilatation. post phaco trab SIA RE 0.21 and LE 0.23 added and Post Phaco SIA 0.5 added in Toric IOL power calculation for Gr1 & Gr2 respectively.Post op 90 days outcomes measure were ACD, Photopic & Mesopic UCDVA, BCDVA, Residual Astigmatism, Spherical equivalent.
Results
Post Op 90 days, Photopic UCVDA mean diff (0.04) between GrI & GrII p= .0001, 95% CI (.038,.042) & BCDVA mean diff (-0.30) p= .0004, 95% CI (-.031, -.029) & Mesopic UCDVA mean diff(.08 ) p= .0001, 95% CI (.045,.11) & BCDVA mean diff( .06,) p= .0008 95% CI (.026,.094) are significantly better in Gr I as compared to Gr II . Residual Spherical Equivalent mean diff (-0.20 ) p = .0001,95%CI(-.21,-.19) & Residual Astigmatism mean diff (0.08) p=.006,95%CI(.03,.12) are significantly less in Gr1. Mean change (pre- 3 month post op) of ACD & IOL between GrI & GrII reveals comparable results. Mean change ACD =0.40,p=.44, 95% CI( -.064,.144) and IOL mean change= -.77, p=.08 95%CI(.09,1.68).
Conclusion
Cataract surgery with Trab results in unpredictable astigmatism due to scaring at the trabeculectomy site and making it difficult to reach zero error with simultaneous Toric IOL implantation. After adding post phaco and trab SIA, we can implant toric IOL at the same sitting with phaco trabeculectomy resulting in optimum refractive results.
Presenting Author
Ehud I. Assia, MD
Co-Authors
Avner Belkin MD
Purpose
To report clinical experience with a modified toric plate-haptic lens (Vistor, Hanita Lenses) designed for scleral fixation in eye with no capsular support.
Methods
The commercial Vistor lens design was modified by adding two holes in the lens haptic to allow 4-point fixation. The lens axis was marked preoperatively, and the insertion points of the sutures were marked 2mm from the limbus and 2mm on each side of the toric marks. Prolene 6-0 sutures were inserted through the sclera and threaded through the designated holes in the IOL haptics. Four-point fixation was achieved by creation of 4 external flanges.
Results
Sixteen lenses were implanted in 12 patients with no capsular support. One patient required repositioning of the sutured lens. The final position of the PC-IOL was 5o or less from intended axis in 87% of the patients. UCVA and BCVA were 20/30 or better in 50% and 93%, respectively. No tilt was noted post operatively.
Conclusion
Four-point fixation of a plate haptic IOL design provides a precise and stable IOL positioning with no tilt. This can be an optimal design for IOLs designated for scleral fixation in eyes with no capsular support.
Presenting Author
Hoseok Chung, MD
Co-Authors
Jae Yong Kim MD, PhD, Hayoung Lee MD, YooYoung Jeon MD, Kyu Sang Eah MD
Purpose
To evaluate the short-term clinical outcomes of a new purely refractive extended depth of focus intraocular lens, Puresee (ZEN00V; Johnson & Johnson, Jacksonville, FL, USA), and to compare it with the diffractive multifocal intraocular lens, Panoptix (CNTW00; Alcon, Fort Worth, TX, USA).
Methods
This retrospective study included patients who underwent posterior chamber intraocular lens implantation and were divided into two groups: ZEN00V group (51 eyes) and CNTW00 group (62 eyes). Preoperative and 1-month postoperative measurements included uncorrected and best-corrected distance, intermediate, and near visual acuity, refractive error, defocus curves, and contrast sensitivity. Additionally, near-vision spectacle dependence and visual symptoms were assessed through questionnaires.
Results
At 1 month postoperative, no significant differences were found in uncorrected and best-corrected distance visual acuity between the two groups (p=0.470, p=0.097). However, the CNTW00 group demonstrated significantly better intermediate and near visual acuity (both p<0.001) and higher visual acuity in defocus curves at -1.5D, -2D, and -2.5D (p=0.001, p=0.001, p=0.003). There were no significant differences in contrast sensitivity under both photopic and mesopic conditions (all p>0.05). The ZEN00V group reported fewer photic symptoms (glare, p=0.012; halo, p=0.001) but higher near-vision spectacles dependence (p=0.021).
Conclusion
The ZEN00V, as a purely refractive extended depth of focus intraocular lens, showed reduced near vision compared to CNTW00, but with fewer photic symptoms. No difference in contrast sensitivity was observed between the groups.
Presenting Author
Gerd U. Auffarth, MD, PhD
Co-Authors
Lizaveta Chychko MD, Lusine Vogormian MD, Oliver Hassel MD, Ramin Khoramnia MD
Purpose
To evaluate the functional outcomes including visual performance and patient reported outcomes after implantation of the refractive EDOF lens Tecnis PureSee DEN00V and TECNIS PureSee Toric II (JnJ, US).
Methods
This ongoing prospective study includes 28 eyes of 14 patients who underwent phacoemulsification with implantation of Tecnis PureSee DEN00V and TECNIS PureSee Toric II (JnJ, US). The mean age of the patients was 69 � 12 years. Postoperative follow-up at 1 and 3 months included uncorrected (UDVA) and corrected (CDVA) distance visual acuity, uncorrected (UIVA) and distance corrected intermediate visual acuity (DCIVA) at 80 cm, and uncorrected (UNVA) and distance corrected near visual acuity (DCNVA) at 40 cm. Binocular best-corrected defocus curve analysis in the range +2 to -4 and halo and glare simulation were evaluated 3 months after surgery.
Results
Mean binocular visual acuity in logMAR at 1 month after surgery was UDVA/ CDVA (0.05/-0.06), UIVA/ CIVA (-0.02/0.00) and UNVA/ CNVA (0.24/ 0.32). Mean binocular visual acuity in logMAR at 3 months follow-up was UDVA/ CDVA (-0.04/ -0.10), UIVA/ CIVA (0.05/ 0.02) and UNVA/ CNVA (0.26/ 0.19). Results indicate that the TECNIS Puresee IOL performs comparably to standard monofocal lenses in terms of contrast sensitivity under photopic and mesopic conditions
Conclusion
Initial results showed good visual acuity and reduced photopic phenomena. In particular, patients reported little or no photopic phenomena in terms of halo and glare simulation. The IOL power calculation for the Tecnis PureSee IOL and the implantation behaviour are uncomplicated.
Presenting Author
Avery W. Zhou, BA, MA
Co-Authors
Eva Liang MD
Purpose
To compare the early surgical outcomes of Clearview 3 Multifocal intraocular lenses (IOLs) versus Vivity non-toric IOLs in conjunction with cataract surgery.
Methods
This is a retrospective single-surgeon study. The initial cases of eyes implanted with Clearview 3 (CV) lenses from 8/14/2023 to present were compared to eyes implanted with Vivity (V) lenses during the same time period. Pre-operative manifest refraction, best-corrected distance visual acuity (BCDVA) and uncorrected distance visual acuity (UCDVA), as well as 1 month post-operative manifest refraction, BCDVA, UCDVA, uncorrected intermediate visual acuity (UCIVA), and uncorrected near visual acuity (UCNVA), were collected. Complications and any visual complaints were noted. Cases that failed to arrive at the 1-month follow-up appointment were removed (2 V cases).
Results
A total of 11 CV and 33 V cases were preliminarily analyzed. The mean pre-op spherical equivalent in the CV cohort was -0.81�3.29 and in the V cohort was -2.07�3.45. Mean post-op spherical equivalent was 0.17�0.40 for CV and -0.12�0.65 for V (p=.17). Post-op UCDVA (CV: 20/23, V: 20/28, p=.18), UCIVA (CV: 20/20, V: 20/24, p=.12), UCNVA (CV: 20/26, V: 20/43, p=.004), and BCDVA (CV: 20/20, V: 20/21, p= .13) revealed a statistically significant difference in UCNVA between the two cohorts. Unwanted visual phenomena were noted in 2/11 CV cases and 2/33 V cases (p=.23). Mild PCO was noted during the 1-month follow-up in 5/11 CV cases and 7/33 V cases (p=.12).
Conclusion
Preliminary data show significantly better UCNVA in CV patients compared to V patients, however BCDVA, UCDVA, and UCIVA were not significantly different at 1-month post-op. More reported unwanted visual phenomena and PCO in those implanted with CV. We are continuing to track and add patients to this cohort for presentation.
Presenting Author
Helga P. Sandoval, MD, MSc
Co-Authors
Richard Potvin OD, Kerry Solomon MD, William Soscia MD, Priya Mathews MPH, MD, Joaquin De Rojas MD
Purpose
To evaluate spectacle independence, patient satisfaction and visual disturbances reported by patients bilaterally implanted with one of two extended depth of focus (EDOF) intraocular lenses (IOLs) after uneventful routine laser assisted cataract surgery with a plano target refraction in both eyes (OU).
Methods
Prospective, randomized, double-masked study that includes 64 patients undergoing bilateral cataract surgery with implantation of an EDOF OU. Patients (pts) were randomized to one of 2 groups: Symfony with OptiBlue or Vivity. Preoperative and at 3-months postoperative, patients complete questionnaires evaluating spectacle independence, patient satisfaction (PRSIQ), and visual disturbances (PRVSQ) and the VFQ-25. Statistical analyses will be used to compare both groups, with a P-value < .05 considered statistically significant.
Results
Thirty-one subjects in each group completed the 3-month study visit. There were no statistically significant differences between the groups regarding the need for, or wearing of, spectacles for distance, intermediate or near vision. Halos and starbursts were more frequently reported with the Symfony lens, but only halos were significantly more bothersome. There was no difference between groups in the difficulty subjects reported from visual disturbances. Non-directed complaints were not significantly different between groups: difficulty reading was the most common complaint. Over 90% of subjects in both groups were completely or mostly satisfied with their distance and intermediate vision.
Conclusion
Directed questionnaires related to spectacle independence, satisfaction and the frequency and bother from visual disturbances showed few statistically significant differences between the two EDOF lenses. Patient satisfaction with distance and intermediate vision was high, with high levels of spectacle independence with both IOLs.
Presenting Author
Rahul T. Pandit, MD, ABO
Purpose
To describe the binocular visual outcomes with a next generation hybrid intraocular lens with multifocal and extended depth of focus diffractive optics.
Methods
A retrospective chart review was conducted of all patients undergoing phacoemulsification with bilateral implantation of a Tecnis Odyseey IOL (DRN00V) or Tecnis Odyssey Toric IOL (DRT150, DRT225, DRT300, and DRT375) (Johnson & Johnson Vision) by a single surgeon (RTP) from June through December 2024. Exclusion criteria included a prior history of keratorefractive surgery, lack of followup beyond 21 days postoperatively, or concurrent ocular conditions limiting best corrected distance visual acuity to ?20/30 Snellen (0.18 logMAR) in either eye. Primary endpoints were uncorrected distance and near visual acuities, and corrected visual acuities at distance, 66 cm, 50 cm, and 33 cm.
Results
A total of 40 eyes of 20 patients were included. Mean age was 66 years, with 56 percent female. Mean followup was 40 days. Mean CDVA improved from 0.227 � 0.161 logMAR preoperatively to 0.00 � 0.00 logMAR postoperatively (p<0.01) mean="" spherical="" equivalent="" improved="" from="" a="" preoperative="" value="" of="" -1.27="" �="" 3.59="" diopters="" to="" a="" postoperative="" value="" of="" -0.05="" �="" 0.21="" diopters="">0.01)><0.01). there="" was="" also="" a="" significant="" improvement="" from="" the="" preoperative="" cdva="" to="" the="" postoperative="" udva="" of="" 0.009="" �="" 0.028="" logmar="">0.01).><0.01). mean="" �="" sd="" logmar="" values="" were="" as="" follows:="" udva="" 0.01="" �="" 0.03,="" unva="" 0.04="" �="" 0.05,="" cdva="" 0.00="" �="" 0.00,="" dcnva="" 0.05="" �="" 0.06,="" dciva-50="" 0.11="" �="" 0.06,="" and="" dciva-66="" 0.19="" �="">0.01).>
Conclusion
The Odyssey IOL achieves an excellent range of vision including distance, intermediate at 66 and 50 cm, and near at 33 cm.
Presenting Author
Han Ul Kim, MD
Co-Authors
Junkyu Chung MD, Won Seok Song MD, Yeokyoung Won PhD, Dong Hui Lim MD, PhD
Purpose
This study aims to report the clinical outcomes and patient satisfaction following cataract surgery using extended depth of focus (EDOF) intraocular lens (IOL): Tecnis� Puresee
Methods
A retrospective analysis was conducted on patients who underwent cataract surgery with the Tecnis� Puresee at Samsung Medical Center. Preoperative and 1,3,6 month postoperative uncorrected and corrected distance visual acuity (UDVA and CDVA), as well as manifest refraction, were evaluated. Additionally, monocular uncorrected intermediate and near visual acuity were measured, along with defocus curves and contrast sensitivity tests. Patient-reported outcomes, including dependence on spectacles or reading glasses, incidence of photic phenomena, and overall satisfaction, were assessed via questionnaire.
Results
A total of 20 eyes were included in the study. Distance uncorrected visual acuity significantly improved from 0.53 before surgery to 0.07 after 1 month of surgery. Distance corrected visual acuity also significantly improved from 0.17 before surgery to 0.03 after 1 month of surgery. Intermediate visual acuity measured at 80 cm and 60 cm was lower than 0.3 at all postoperative periods. The defocus curve also showed good far and intermediate visual acuity of over 0.2 up to -2D, but showed a decreasing trend at lower diopters. Contrast sensitivity results before and after surgery stayed within the normal range.
Conclusion
This retrospective study confirmed the postoperative clinical outcomes of Tecnis� Puresee. It showed good distance and intermediate visual acuity after surgery. It also showed excellent results in dysphotopsia, suggesting that Tecnis� Puresee would be an excellent option for improving intermediate visual acuity after cataract surgery.
Presenting Author
Anuradha Ondhia, OD
Co-Authors
Ike Ahmed FRCSC, MD, Mohammed Ghanbarnia BSc
Purpose
To assess and compare the visual and refractive outcomes of the Clareon Vivity (hydroxyethyl methacrylate) and Acrysof Vivity (phenylethyl methacrylate) IOLs following bilateral implantation in patients undergoing cataract surgery.
Methods
This is a prospective,randomized, double-masked,comparative study on adults 45+ with bilateral cataracts (graded 2 to 3). Patients must have minimum visual potential of 20/25 monocularly and otherwise clear media. Routine bilateral small incision lens removal was performed a max of 2 months apart, targeting �0.50 D in the non-dominant eye. Outcome measurements at 3-month: binocular mesopic and photopic CS without glare and mesopic CS with glare(CSV 2000); binocular target corrected and UCVA at distance, intermediate (66cn) , and near (40 cm)in photopic conditions. Further outcomes: patient reported outcomes (using QUVID� and IOLSAT�) to evaluate visual disturbances and patient satisfaction.
Results
TBD
Conclusion
TBD
Presenting Author
Wisam O. Najdawi, BSc
Co-Authors
Zachary Mortensen MD, MBA, Jaclyn Haugsdal MD, Thomas Oetting MD, Tirth Shah MD
Purpose
To compare refractive outcomes, visual acuity, and post-operative complication rates in resident- versus faculty-performed cataract surgery with toric intraocular lens (IOL) placement.
Methods
The surgical log of a single faculty ophthalmologist was reviewed to identify patients who underwent cataract surgery with toric IOL placement. Surgeries were classified as resident- or faculty-performed based on the primary surgeon. Primary outcome measures included residual post-operative cylindrical power (CYL), post-operative uncorrected distance visual acuity (UCDVA), and post-operative complication rates. Statistical analyses were conducted using two-sample t-tests or Wilcoxon rank-sum tests, as appropriate (
Results
155 eyes from 110 patients (age=71.7�11.7 years, 45.8% male) were identified. In these cases, a resident performed 134 (86.5%) and faculty performed 21 (13.5%). The pre-operative corneal CYL was 1.81�1.05 D in resident cases and 1.82�0.77 D in faculty cases (p=0.59). The residual post-operative CYL was 0.55�0.54 D in resident cases and 0.54�0.54 D in faculty cases (p=0.86). The post-operative UCDVA (logMAR) was 0.21�0.28 in resident cases and 0.20�0.26 in faculty cases (p=0.93). Post-operative complications occurred in 5 resident cases (3.7%), including 4 cases of cystoid macular edema (CME) and 1 rotated lens requiring repositioning, and 1 faculty case (4.8%), 1 case of CME (p=0.96).
Conclusion
There were no significant differences in post-operative refractive outcomes, post-operative UCDVA, or post-operative complication rates between resident- and faculty-performed cataract surgeries with toric IOL implantation. Toric IOL implantation by residents is a safe and effective surgical procedure.
Presenting Author
Byung Yi Ko, MD, PhD
Co-Authors
Seongjun Lee MD, PhD
Purpose
To evaluate the postoperative clinical outcomes after cataract surgery with implantation of a new extended depth of focus (EDOF) IOL.
Methods
We analyzed retrospectively 25 eyes of 16 patients, who underwent cataract surgery with Tecnis PureSee� (Johnson ? Johnson Vision, Santa Ana, CA, USA) from Apr to Jun in 2024. We assessed visual acuity using the logarithm of the minimal angle of resolution (logMAR) scale and evaluated the visual performance including uncorrected distance visual acuity (UDVA), uncorrected intermediate visual acuity (UIVA), uncorrected near visual acuity (UNVA) and the defocus curve at 1 month postoperatively. In addition, we administered a satisfaction questionnaire at 1 month postoperatively.
Results
At 1 month postoperatively, monocular UDVA, UIVA, UNVA results were 0.05 � 0.06, 0.35 � 0.08 and 0.34 � 0.08, respectively. The results exhibited good VA better than 0.35 in the monocular DC and VA above 0.20 in the binocular DC in the range of +1.00 diopters (D) to -1.50 D. In the questionnaire, overall satisfaction responses for VA were 8.2 in distance, 7.9 in intermediate and 6.2 in near. The need for spectacles postoperatively were no (62%), sometimes (31%), the indication for reading glasses postoperatively were no (39%), sometimes (54%). Photic phenomena were reported by patients: no (46%), yes (54%) and halo was dominant photic phenomenon.
Conclusion
PureSee� EDOF IOL achieves good visual performances in far and intermediate distances. The patients do not need reading glasses in 39%, additionally.
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